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Since January 1st 2011, R-Biopharm AG took over the Premi®Test business from DSM. Premi®Test is a microbial screening test for the detection of antibiotic residues in various animal food products.

Premi®Test is a microbial screening test for the detection of antibiotic residues in various animal food products in less than 4 hours. Premi®Test allows to screen meat (beef, pork, poultry), fish, shrimps, eggs, liver, kidney, honey, plasma/serum, urine and feed for the residues of ß-lactams, Cephalosporines, Macrolides, Tetracyclines, Sulphonamides, Aminoglycosides, Quinolones, Amphenicoles and Polypeptides. For the analysis of meat, Premi®Test is certified by AOAC (Licence no: 060601) and AFNOR (no.: DSM-28/1-06-06).

Treatment of farm animals with veterinary pharmaceuticals such as antibiotics leads to drug residues in the tissues of the animals and establishes a health risk for the consumers of animal food products. Premi®Test is an easy antibiotics residue screening test which allows fast screening of food products by all members of the food production chain such as farmers, slaughterhouses, meat-processors and analytical laboratories.
Premi®Test is based on the inhibition of the growth of Bacillus stearothermophilus, a thermophilic bacterium which is very sensitive to many antibiotics and sulpha compounds. A standardised number of spores are imbedded in agar medium containing selected nutrients. When Premi®Test is heated at 64 °C, the spores will germinate. If no inhibitory substances are present the germinated spores will multiply with the production of acid. This will be visible by a colour change from purple to yellow. When anti-microbial compounds are present in sufficient amount (above the detection limit) the spores will be unable to germinate and therefore no colour change will be observed.

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