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Since September 2013, residues of the antibiotic chloramphenicol have been detected in various imported enzyme products by the Rapid Alert System for Food & Feed of the European Union (RASFF). As the enzyme products were intended to be used in production of food and drinks (e.g. wine), the occurrence of chloramphenicol traces can, despite the use of the enzymes in small amounts, not completely excluded. Although it is assumed that there is no direct health risk for the consumer of potentially contaminated foodstuff at the moment, the laws of the European Union demand, that food must be completely free of prohibited substances such as chloramphenicol at any time. Therefore, R‑Biopharm developed a new method for the screening of chloramphenicol in enzymes, wine and grape juice with detection limits below the Minimum Required Performance Limit (MRPL) of 300 ng/kg (ppt).

The combination of immunoaffinity clean-up by RIDA® Chloramphenicol column (R1508) and analysis by RIDASCREEN® Chloramphenicol ELISA (R1505) allows an easy and sensitive screening of enzymes, wine and grape juice for residues of chloramphenicol.

Download Application Note and Validation Report for wine and grape juice

Download Application Note and Validation Report for enzymes

R-Biopharm Rhone is currently preparing a sample preparation protocol for the confirmatory analysis of chloramphenicol in wine by LC/MS. For inquiries please contact: info@r-biopharmrhone.com

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