MS Hub: Multi-toxin analysis with LC-MS/MS detection
Precision mycotoxin sample clean-up and quality assurance
MS Hub: Precision mycotoxin sample clean-up and quality assurance
Multi-toxin analysis with LC-MS/MS detection offers many advantages
LC-MS/MS allows for the simultaneous detection of multiple mycotoxins in a single run, making it highly efficient compared to traditional methods that often target individual mycotoxins. The ability to streamline processes, reduce resource consumption and improve data quality makes it an attractive option across various industries. As technology advances, multi-toxin analysis is poised to play an increasingly critical role in achieving economic and environmental goals.
Often just a minimal sample clean-up is used (“dilute and shoot”) before injection of the LC-MS/MS, which is of course very cost-effective, simple and fast, but has its limitations due to unpredictable matrix effects like signal suppression or signal boosting and lower sensitivity. Besides injecting diluted samples directly into the LC system may increase the need for instrument maintenance.
QuEChERS, which is an acronym for Quick, Easy, Cheap, Effective, Rugged and Safe, can give a better clean-up and offer the option to use one extraction method for different types of analysis besides mycotoxins, for instance, pesticides, but are more laborious and often still insufficient to eliminate matrix effect. Therefore, we developed the concept of MS-Hub, a combination of precision clean-up and quality assurance tools, powered by mycotoxin testing expertise.
MS Hub – All-in-one sample clean-up and quality assurance tools for mycotoxin testing
We are pleased to announce our MS Hub designed specifically for LC-MS/MS users to further enhance our commitment to ensure simple and efficient mycotoxin sample processing. With these offerings, we aim to provide laboratories, researchers and industry with everything they need for accurate, efficient and reliable mycotoxin analysis for LC-MS/MS from a single source.
MS Hub is comprised of two areas, focussed on sample clean-up and quality assurance
QuantPREP™
Highly effective clean-up tools prior to mycotoxin analysis by LC-MS/MS
• Immunoaffinity columns
• Solid phase columns
• Automated systems
QualiT™
Quality assurance tools in mycotoxin analysis
• Analytical Standards
• Quality Control Materials
• Analytical Services
Learn more and download this brochure about MS Hub: Precision mycotoxin sample clean-up and quality assurance, powered by mycotoxin testing expertise
R-Biopharm’s RBR Immunoaffinity Columns and QualiT Pure Solid Phase Columns offer a superior alternative to using QuEChERS or dilute-and-shoot, providing a more effective clean-up for all kinds of samples
Effective Clean-Up for All Sample Types:
One of the standout benefits of RBR Immunoaffinity Columns and QualiT Pure Solid Phase Columns is their ability to provide an effective clean-up across a wide range of sample types. Whether you are dealing with complex matrices like grains, nuts or dairy products, these tools ensure interfering substances are efficiently removed, leaving you with a clean sample ready for precise analysis. This level of clean-up is crucial for obtaining accurate and reproducible results, especially when dealing with low levels of mycotoxins.
Ease of Use:
Another significant advantage is the ease of use. Both RBR Immunoaffinity Columns and QualiT Pure Solid Phase Columns are designed with user-friendliness in mind. The protocols are straightforward, reducing the risk of errors and saving valuable time in the laboratory. This simplicity does not compromise the quality of the results; instead, it enhances the overall efficiency of the analytical process.
Versatility:
Versatility is a key feature of these sample clean-up tools. They are not limited to a specific type of mycotoxin or sample matrix. This flexibility allows laboratories to streamline their workflows, using the same clean-up tools for various analyses. This not only simplifies inventory management but also ensures consistency in the quality of the results across different types of samples.
Superior to Traditional Methods:
While dilute and shoot and QuEChERS are commonly used methods, they often require additional steps or adjustments to handle different sample types effectively. These methods can lead to matrix interferences, such as signal suppression or signal boosting, which can compromise the accuracy of the results. RBR Immunoaffinity Columns and QualiT Pure Solid Phase Columns, on the other hand, offer a more streamlined and reliable approach. The use of these advanced clean-up tools minimizes matrix effects and enhances the sensitivity and specificity of the LC-MS/MS analysis.
Advantages of Matrix-Matched Calibration for mycotoxin analysis by LC-MS/MS
Using matrix-matched calibration with Trilogy mycotoxin quality control materials and Trilogy mycotoxin standards offers several advantages over stable isotope labeled mycotoxin standard addition:
Reduced Matrix Effects:
Matrix-matched calibration helps to compensate for matrix effects that can influence the analytical response, leading to more accurate and reliable results.
Ease of Use:
Matrix-matched calibration is less laborious and time-consuming compared to the stable isotope dilution assay (SIDA), which requires the addition of stable isotope labeled standards.
Versatility:
Trilogy mycotoxin quality control materials and standards are designed to be compatible with a wide range of matrices, making them suitable for various types of samples.
Consistency:
Using matrix-matched calibration ensures that the calibration standards closely mimic the sample matrix, leading to consistent and reproducible results.
Conclusion
In conclusion, the RBR Immunoaffinity Columns and QualiT Pure Solid Phase Columns represent a significant advancement in the field of mycotoxin analysis. Their ability to provide effective clean-up for all kinds of samples, combined with ease of use and versatility, makes them superior to traditional methods. Additionally, the use of matrix-matched calibration with Trilogy mycotoxin quality control materials and standards offers further benefits in terms of accuracy, ease of use and consistency. By incorporating these tools into your laboratory workflow, you can achieve more accurate, reliable and efficient mycotoxin analysis.
Explore the benefits of RBR Immunoaffinity Columns, QualiT Pure Solid Phase Columns and Trilogy mycotoxin standards today and elevate your mycotoxin analysis to the next level.
R-Biopharm – your partner in food analysis.
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Get in touch with our mycotoxin experts to implement multi-toxin analysis with LC-MS/MS detection with our all-in-one sample clean-up and quality assurance tools.
