Residues and contaminants

Detection of antibiotic, hormone and anabolic residues in food

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Analytes

Residues and contaminants: Monitoring and analysis

Importance of monitoring residues and contaminants

When food-producing animals are treated with antibiotics, hormones, or anabolics, drug residues can remain in the animal’s meat and milk, posing health risks to consumers. “Residues are the remains of substances which are intentionally used during the production of foods” (Source: BFR). These include veterinary drugs and pesticides. To protect consumers, many countries have established maximum residue limits (MRLs) and monitoring programs.

Analytical solutions for residue detection

Our product portfolio includes various test systems for detecting hormones, anabolics, antibiotics, and other drug residues in different matrices. These systems include:

  • Enzyme immunoassays (ELISAs)
  • Microbial inhibition tests
  • Immunoaffinity columns

Categories of residues and contaminants

Antibiotics

Antibiotics are naturally occurring metabolites derived from fungi or bacteria. They can also be produced through modern biotechnology and chemical synthesis. Antibiotics kill microorganisms or inhibit their growth and are used in human and veterinary medicine to treat bacterial diseases.

Hormones and anabolics

Residues of hormones and anabolic steroids in foods such as meat and milk pose potential health risks to consumers. Hormones are endogenous biochemical messengers transported through the bloodstream to target organs. Synthetic steroids and beta-agonists are used in livestock breeding to improve average weight gain and the meat/fat ratio.

Other veterinary drugs

In addition to antibiotics and anabolics, animals may be treated with other veterinary drugs, leading to residues in food. These drugs include:

  • Fungicides: Used to kill or inhibit fungi.
  • Anthelmintics: Used to treat infections with parasitic worms.
  • Corticosteroids: Synthetic steroid hormones supporting various physiological functions.
  • Tranquilizers: Used to prevent transport illness and stress syndrome in pigs.
  • Coccidiostats: Used to treat or prevent the parasitic disease coccidiosis.

Chemical contaminants

Chemical contamination of food is a health concern and can result from various sources, including migration from packaging materials. For example, bisphenol A (BPA), used in the production of polycarbonate plastics, can migrate into foods from plastic bottles or packaging. EU legislation has defined a specific migration limit (SML) for BPA to address this issue.

Key benefits of residue and contaminant monitoring

  • Consumer protection: Ensures food products are safe for consumption by detecting and quantifying residues and contaminants.
  • Regulatory compliance: Helps manufacturers comply with MRLs and other food safety regulations, preventing legal and economic repercussions.
  • Quality assurance: Maintains the integrity and safety of food products by preventing the distribution of contaminated items.
  • Advanced detection methods: Utilizes reliable and efficient analytical platforms for the accurate monitoring of various residues and contaminants in food products.

Conclusion

Monitoring residues and contaminants is essential for protecting consumer health, ensuring regulatory compliance, and maintaining the quality of food products. By employing advanced detection methods, manufacturers can accurately identify and quantify harmful substances, ensuring the safety of their products. This proactive approach supports robust quality control processes, upholds food safety standards, and fosters consumer trust in food products.

Product portfolio

ProductDescriptionNo. of tests/amountArt. No.
EuroProxima Multi-Sulfonamides

EuroProxima Sulfonamides is a competitive enzyme immunoassay for quantitative analysis of a broad range of sulfonamides in urine, tissue, milk, egg, honey and shrimps.

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Microtiter plate with 96 wells (12 strips with 8 individual wells each) 5101SULM
RIDASCREEN® Nitrofuran (DNSH)

RIDASCREEN® Nitrofuran DNSH (Art. No. R3725) is a competitive enzyme immunoassay for the quantitative determination of the Nifursol metabolite 3,5-dinitrosalicylic acid hydrazide (DNSH) in shrimp.

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Microtiter plate with 96 wells (12 strips with 8 individual wells each) R3725
EuroProxima Trimethoprim ELISA

The Trimethoprim ELISA is a competitive enzyme immunoassay based on antibodies directed against trimethoprim.

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Microtiter plate with 96 wells (12 strips with 8 removable wells each) 5101TMP
EuroProxima DNSH

EuroProxima DNSH is a competitive enzyme immunoassay for the quantitative detection of nifursol metabolite 3,5-dinitrosalicylic acid hydrazide (DNSH) in meat and seafood.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5091DNSH
RIDASCREEN® DNSH

RIDASCREEN® DNSH (Art. No. R3740) is a competitive enzyme immunoassay for the quantitative analysis of nifursol metabolite 3,5-dinitrosalicylic acid hydrazide (DNSH) in meat (poultry, pork, beef) and seafood (fish, shrimp, and prawn).

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3740
EuroProxima Tetrodotoxin Sensitive

EuroProxima Tetrodotoxin Sensitive is a competitive enzyme immunoassay for quantitative analysis of tetrodotoxin in fish and shellfish. A higher sensitivity for the detection of Tetrodotoxin With the introduction of the EuroProxima 5191TTXSens …

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5191TTXSens
RIDASCREEN® Nitrofuran (SEM)

RIDASCREEN® Nitrofuran (SEM) (R3724) is a competitive enzyme immunoassay for the quantitative analysis of semicarbazide (SEM) in shrimp, fish, meat (bovine, porcine and chicken).

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Microtiter plate with 96 wells (12 strips with 8 wells each). R3724
EuroProxima Ethinylestradiol

EuroProxima Ethinylestradiol is a competitive enzyme immunoassay (ELISA) for screening and quantitative analysis of ethinylestradiol in tissue, plasma/serum and urine.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5081ESTR
EuroProxima Nortestosterone

EuroProxima Nortestosterone is a competitive enzyme immunoassay for screening and quantitative analysis of 19-Nortestosterone in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5081NOR
EuroProxima Methyltestosteron

EuroProxima Methyltestosteron is a competitive enzyme immunoassay for screening and quantitative analysis of methyltestosterone in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5081MTES
EuroProxima Florfenicol

EuroProxima Florfenicol is a competitive enzyme immunoassay for the screening and quantitative detection of florfenicol in different commodities.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5091FLORF
EuroProxima Oxolinic Acid

EuroProxima Oxolinic acid is a competitive enzyme immunoassay for the screening and quantitative detection of oxolinic acid in fish, shrimp and prawn.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5101OXO
EuroProxima Okadaic Acid

EuroProxima Okadaic Acid is a competitive enzyme immunoassay for quantitative analysis of domoic acid in scallop, mussel and oyster samples.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5191OKA
EuroProxima Tetrodotoxin

EuroProxima Tetrodotoxin is a competitive enzyme immunoassay for quantitative analysis of tetrodotoxin in fish and shellfish.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5191TTX
EuroProxima Zeranol

This competitive enzyme immunoassay is used for the quantitative determination of zeranol in urine, tissue and liver.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5081ZERAN
EuroProxima Medroxyprogesterone Acetate

A competitive enzyme immunoassay for screening and quantitative analysis of medroxyprogesterone acetate (MPA) in bovine kidney fat.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5131MPA
EuroProxima Trenbolone

This competitive enzyme immunoassay is used for the quantitative determination of trenbolone in urine, liver and tissue.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081TRENBO
EuroProxima Florfenicol-amine

A competitive enzyme immunoassay for screening and quantitative analysis of florfenicol-amine in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5091FLOA
EuroProxima Neomycin

A competitive enzyme immunoassay for screening and quantitative analysis of neomycin in milk, milk powder, tissue, honey, serum/plasma and urine samples.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5111NEO
EuroProxima Oxytetracycline

A competitive enzyme immunoassay for screening and quantitative analysis of oxytetracyclines in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5091OTC
EuroProxima Tylosin

EuroProxima Tylosin is a competitive enzyme immunoassay for screening and quantitative analysis of tylosin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5151TYL
EuroProxima Virginiamycin

EuroProxima Virginiamycin is a competitive enzyme immunoassay for quantitative analysis of virginiamycin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5151VIG
EuroProxima Fluoroquinolones

EuroProxima Fluoroquinolones is a competitive enzyme immunoassay for screening and quantitative analysis of a broad range of fluoroquinolones in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5101FLUQG
EuroProxima Fluoroquinolones II

EuroProxima Fluoroquinolones II is a competitive enzyme immunoassay for screening and quantitative analysis of fluoroquinolones in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5101FLUQII
EuroProxima Promazine, generic

EuroProxima Promazine, generic is a competitive enzyme immunoassay for screening and quantitative analysis of several promazines in tissue, liver, urine and kidney.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5201PROM
EuroProxima Malachite Green Total/Crystal Violet

EuroProxima Malachite Green Total/Crystal Violet is a competitive enzyme immunoassay for quantitative analysis of malachite green, leucomalachite green, crystal violet and leucocrystal violet in fish and shrimp.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5161MGT
EuroProxima Azaperone-Azaperol

EuroProxima Azaperone-Azaperol is a competitive enzyme immunoassay for screening and quantitative analysis of azaperone/azaperol in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5201AZA
EuroProxima Carazolol

EuroProxima Carazolol is a competitive enzyme immunoassay for screening and quantitative analysis of carazolol in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5201CARA
EuroProxima Corticosteroid

This competitive enzyme immunoassay is used for the quantitative determination of corticosteroids in milk, urine, muscle, liver and feed.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081COR
EuroProxima Progesterone

This competitive enzyme immunoassay is used for the quantitative determination of progesterone in milk and serum.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081PROG
EuroProxima Stanozolol

This competitive enzyme immunoassay is used for the quantitative determination of stanozolol in urine and faeces.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081STAN
EuroProxima Triamcinolone

This competitive enzyme immunoassay is used for the quantitative determination of triamcinolone in urine.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081TRIA
EuroProxima Saxitoxin

EuroProxima Saxitoxin is a competitive enzyme immunoassay for the screening and quantitative analysis of the shellfish poison saxitoxin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5191SAXI
EuroProxima Lincomycin

A competitive enzyme immunoassay for screening and quantitative analysis of lincomycin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5151LIN
EuroProxima Gentamicin

A competitive enzyme immunoassay for screening and quantitative analysis of gentamicin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5111GEN
EuroProxima Flumequine

EuroProxima Flumequine is a competitive enzyme immunoassay for screening and quantitative analysis of flumequine in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5101FLUM
EuroProxima Erythromycin

EuroProxima Erythromycin is a competitive enzyme immunoassay for screening and quantitative analysis of erythromycin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5151ERY
EuroProxima Domoic Acid

EuroProxima Domoic Acid is a competitive enzyme immunoassay for quantitative analysis of domoic acid in scallop, mussel and oyster samples.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5191DOMO
EuroProxima Dimetridazole

EuroProxima Dimetridazole is a competitive enzyme immunoassay for quantitative analysis of dimetridazole in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5091DIME
EuroProxima Colistin

A competitive enzyme immunoassay for screening and quantitative analysis of colistin in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5151COL
EuroProxima Ivermectin

EuroProxima Ivermectin is an unique competitive enzyme immunoassay (ELISA) for the detection of ivermectin in urine, tissue and milk samples.

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Microtiter plate with 96 wells (12 strips with 8 wells each). 5141IVER
EuroProxima Diethylstilbestrol (DES)

A competitive enzyme immunoassay for screening and quantitative analysis of diethylstilbestrol (DES) in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5081DES
EuroProxima Penicillin

A competitive enzyme immunoassay for screening and quantitative analysis of penicillins in various matrices.

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Microtiter plate with 96 wells (12 strips with 8 wells each) 5091PEN
RIDASCREEN® Tetracyclin

RIDASCREEN® Tetracyclin is a competitive enzyme immunoassay for the quantitative analysis of tetracyclins in milk, milk powder, cheese, butter, dairy products (curd, yoghurt (plain/with fruits), kefir, cream, sour cream) honey, meat, sausage, fish, …

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3505
RIDASCREEN® Chloramphenicol

RIDASCREEN® Chloramphenicol is a competitive enzyme immunoassay for the quantitative analysis of chloramphenicol in milk, milk powder and dairy products, honey and royal jelly, meat, fish, shrimp, eggs, urine (also chloramphenicol glucuronide), …

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Microtiter plate with 96 wells (12 strips with 8 wells each) R1511
RIDASCREEN® Sulfamethazin

RIDASCREEN® Sulfamethazin is a competitive enzyme immunoassay for the quantitative determination of sulfamethazine in milk, meat, honey, liver, kidney, fish, shrimp and egg.

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Microtiter plate with 96 wells (12 strips with 8 wells each). R3011
RIDASCREEN® Streptomycin

RIDASCREEN® Streptomycin is a competitive enzyme immunoassay for the quantitative analysis of streptomycin in milk and milk powder, honey, meat, liver, kidney, shrimp and apple juice.

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Microtiter plate with 96 wells (12 strips with 8 wells each). R3104
RIDASCREEN® Bacitracin

RIDASCREEN® Bacitracin is a competitive enzyme immunoassay for the quantitative analysis of bacitracin in milk, meat, eggs, feed and urine.

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Microtiter plate with 96 wells (12 strips with 8 removable wells each). R2901
RIDASCREEN® Clenbuterol

RIDASCREEN® Clenbuterol is a competitive enzyme immunoassay for the quantitative analysis of clenbuterol in milk, meat, liver, kidney, urine, plasma/serum, hair, eyeball and feed.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R1711
RIDASCREEN® β-Agonists

RIDASCREEN® β-Agonists is a competitive enzyme immuno­assay for the quantitative analysis of β-Agonists in urine, serum, meat, liver, milk and feed.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R1704
RIDASCREEN® Ractopamin

RIDASCREEN® Ractopamin is a competitive enzyme immunoassay for the quantitative analysis of ractopamine in urine, meat and liver and for the qualitative analysis of ractopamin glucuronide in urine.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R9901
RIDASCREEN® Nitrofuran (AHD)

RIDASCREEN® Nitrofuran (AHD) is a competitive enzyme immunoassay for the quantitative analysis of the nitrofurantoin metabolite AHD in shrimp and fish.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3713
RIDASCREEN® Nitrofuran (AMOZ)

RIDASCREEN® Nitrofuran (AMOZ) is a competitive enzyme immunoassay for the quantitative determination of AMOZ in shrimp, fish, meat and poultry.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3722
RIDASCREEN® Nitrofuran (AOZ)

RIDASCREEN® Nitrofuran (AOZ) is a competitive enzyme immunoassay for the quantitative analysis of AOZ in shrimp, meat (chicken, pork, beef), liver (beef and pork), fish, whole egg and milk.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3703
RIDASCREEN® Chinolone/Quinolones

RIDASCREEN® Chinolone/Quinolones is a competitive enzyme immunoassay for the quantitative analysis of chinolones in egg, meat (beef, pork, sheep, chicken, turkey), fish and shrimp.

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Microtiter plate with 96 wells (12 strips with 8 wells each) R3113
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ProductDescriptionNo. of tests/amountArt. No.
Premi®Test Urin

Premi®Test Urin is a reagent that enables bovine/porcine urine to be tested for antibiotic residues with Premi®Test.

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Premi®Test Urine contains 1 dropping bottle with 15 ml of sample buffer. The number of samples which can be prepared is dependent on the volume of the samples. Exemplarily, 30 samples with a volume of 30 ml each. R3921
Premi®Test 25

Premi®Test is a microbial screening test that allows the detection of antibiotic residues, especially in fresh meat (beef, pork, poultry) in less than 4 hours. The test is sensitive to antibiotics of the following groups: β-lactams, cephalosporins, …

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25 ampoules R3925
Premi®Test 4×25

Premi®Test is a microbial screening test that allows the detection of antibiotic residues, especially in fresh meat (beef, pork, poultry) in less than 4 hours. The test is sensitive to antibiotics of the following groups: β-lactams, cephalosporins, …

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4 x 25 ampoules R3900
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ProductDescriptionNo. of tests/amountArt. No.
RIDA® C18 column

The solid phase extraction (SPE) with RIDA® C18 columns is an efficient technique for a fast and selective sample preparation, especially for the RIDASCREEN® and EuroProxima anabolic- and hormone enzyme immunoassays.

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100 x C18 columns (100 mg/ml column reservoir) R2002
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